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Persians in the 6th century BC. Üsküdar was
subsequently ruled in turn by the Athenians,
Spartans and Bithynia, before becoming part
of the Roman Empire in 74 BC. Under both Romans
and Byzantines, Üsküdar appears to have been
an insignificant village. Professor Dr Semai
Eyice, in his book about the Bosphorus in the
Byzantine period, writes that the only large
buildings of importance here were the monasteries
of Chrysopolis and Philippicos, of which there
is no trace today. Nor does anything remain
of the few small monasteries and places of worship
here. The largest monastery no longer existed
in the 10th century, and the remainder had disappeared
one by one by the 14th century. So, prior to
Ottoman times, Üsküdar had lost what importance
it had and was diminishing in size. In 1347
the second Turkish sultan Orhan Gazi, who married
the daughter of the Byzantine emperor John VI
Cantacuzene, met with his father-in-law in Üsküdar,
and in 1352 took possession of this area when
the Genoese, who controlled Pera, were defeated
by the Venetians and requested Orhan Gazi's
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