Lyon - Istanbul flights from EUR246*

Connecting Europe and Asia, Istanbul is an ancient city with a beauty that transcends continents. As one of the world's most popular tourist destinations, Istanbul attracts millions of visitors each year, who come to see the city’s monumental historic structures and to savor its cosmopolitan atmosphere and vibrant cultural and culinary scenes. Check out Lyon-Istanbul flight tickets and come experience Istanbul’s many attractions!

Book flights from Lyon to Istanbul

cmp-daily-histogram-bars-legend-min-price-aria-label EUR259
cmp-daily-histogram-bars-legend-max-price-aria-label EUR511
Displaying fares for October-2026
  • LYS–IST, Tue, October 13 – Tue, October 20: From EUR448
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  • LYS–IST, Wed, October 14 – Sun, October 18: From EUR417
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  • LYS–IST, Thu, October 15 – Mon, October 19: From EUR448
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  • LYS–IST, Fri, October 16 – Tue, October 20: From EUR483
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  • LYS–IST, Sat, October 17 – Mon, October 19: From EUR412
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  • LYS–IST, Sun, October 18 – Sat, October 24: From EUR511
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  • LYS–IST, Mon, October 19 – Mon, November 02: From EUR474
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  • LYS–IST, Tue, October 20 – Tue, November 03: From EUR390
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  • LYS–IST, Wed, October 21 – Wed, November 04: From EUR333
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  • LYS–IST, Thu, October 22 – Thu, November 05: From EUR333
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  • LYS–IST, Fri, October 23 – Fri, November 06: From EUR333
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  • LYS–IST, Sat, October 24 – Sat, November 07: From EUR370
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  • LYS–IST, Sun, October 25 – Sun, November 08: From EUR327
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  • LYS–IST, Mon, October 26 – Mon, November 09: From EUR317
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  • LYS–IST, Tue, October 27 – Fri, November 06: From EUR282
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  • LYS–IST, Thu, October 29 – Thu, November 05: From EUR298
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  • LYS–IST, Sat, October 31 – Wed, November 04: From EUR295
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  • LYS–IST, Sun, November 01 – Sun, November 08: From EUR327
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  • LYS–IST, Mon, November 02 – Mon, November 09: From EUR317
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  • LYS–IST, Tue, November 03 – Tue, November 17: From EUR274
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  • LYS–IST, Fri, November 06 – Sun, November 08: From EUR359
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  • LYS–IST, Sat, November 07 – Sat, November 14: From EUR349
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  • LYS–IST, Sun, November 08 – Tue, November 24: From EUR294
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  • LYS–IST, Mon, November 09 – Fri, November 13: From EUR333
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  • LYS–IST, Tue, November 10 – Tue, November 24: From EUR259
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  • LYS–IST, Wed, November 11 – Wed, November 25: From EUR259
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  • LYS–IST, Thu, November 12 – Tue, November 17: From EUR269
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    Destination 1

    Departure: Lyon

    Set on an island in the middle of the Rhone and Saone rivers, Lyon offers a relaxed atmosphere away from the Paris tourist circuit. Lyon is a genuine gourmet capital, and its famous Bouchon cuisine is worth discovering, while each corner of the city showcases homegrown cultural and literary elements such as Puppet Guignol and The Little Prince. As France's third largest city and a former capital of the silk trade, Lyon was designated a UNESCO World Heritage Site in 1998, a testament to its aesthetic architecture and historical significance. Some Lyon highlights include Fourviere Hill, accessed via a delightful funicular ride; the mysterious Croix Rousse, with more than 400 secret passages; Notre Dame de Fourviere Basilica; and Le Petit Musée Fantastique de Guignol.

    Arrival: Istanbul

    Turkish Airlines offers direct flights from Lyon to Istanbul, an ancient city whose beauty spans two continents. Flights take around three hours and 20 minutes. Istanbul, one of the world's most popular tourist destinations, welcomes millions of visitors each year, who come to view the city’s historic structures and bask in its cosmopolitan atmosphere. Some of Istanbul’s most notable highlights include the magnificent Hagia Sophia; Topkapı Palace, one of the Ottoman Empire's emblematic complexes; the Süleymaniye Mosque, a masterpiece by Mimar Sinan; and the Grand Bazaar, among the world's oldest and largest markets. We recommend visiting the Beyoğlu, Nişantaşı and Kadıköy neighborhoods to experience Istanbul's modern face and a culinary culture that embraces everything from street snacks to Michelin-starred restaurants.

    Destination 1

    Discover Lyon - Istanbul flights

    View current Lyon – Istanbul flight ticket fares to find the flight that’s best for you. Whether you’re flying for business or for leisure, you’ll enjoy a safe, comfortable trip with the exceptional service standards offered by Turkish Airlines.

    EUR
    Discover Lyon - Istanbul flights
    From
    To
    Fare Type
    Dates
    Price
    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Tue, November 24 - Tue, December 01

    From

    EUR246

    Last update 16 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Sat, December 05 - Sat, December 12

    From

    EUR246

    Last update 13 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Thu, December 31 - Thu, January 14

    From

    EUR246

    Last update 10 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Fri, December 04 - Wed, December 09

    From

    EUR246

    Last update 20 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Thu, January 14 - Mon, January 18

    From

    EUR246

    Last update 23 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Tue, January 05 - Tue, January 12

    From

    EUR246

    Last update 23 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Wed, January 06 - Wed, January 20

    From

    EUR246

    Last update 23 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy
    Tue, December 01 - Tue, December 08

    From

    EUR246

    Last update 23 hrs ago

    *Fares displayed have been collected within the last 48 hours and may no longer be available at time of booking.

    Airport information

    Lyon-Saint Exupéry Airport (LYS)

    Turkish Airlines operates Lyon-Istanbul flights from Lyon-Saint Exupéry Airport (LYS). The airport is about 25 kilometers from the city center and accessible via metro, bus or taxi, as well as private vehicle or car sharing. Rhônexpress trains and bus lines 47 and 48 operate between the Lyon city center and the airport.


    Istanbul Airport (IST)

    Located in Arnavutköy, on Istanbul's European side, Istanbul Airport is approximately 42 kilometers from the Istanbul city center. After landing at the airport from Lyon, you can reach the city center via the metro, taxis, municipal buses or airport shuttle buses or by renting a car. The IETT buses, numbered H-1, H-2, H-3, H-6, H-8, and the Gayrettepe - Istanbul Airport metro (M11) are convenient public transportation options operating between the airport and the city, as are the Havaist airport shuttles, which offer service to Istanbul Airport. Taxis are available 24-7 at the airport; the fare and length of the ride will depend according to your destination. In addition, you can rent a car at the airport.

    Frequently Asked Questions