Lyon - Istanbul flights from EUR246*

Connecting Europe and Asia, Istanbul is an ancient city with a beauty that transcends continents. As one of the world's most popular tourist destinations, Istanbul attracts millions of visitors each year, who come to see the city’s monumental historic structures and to savor its cosmopolitan atmosphere and vibrant cultural and culinary scenes. Check out Lyon-Istanbul flight tickets and come experience Istanbul’s many attractions!

Book flights from Lyon to Istanbul

Aug 2026
FromEUR407*
Last update 2 hrs ago
Flight Type Round Trip/Economy
Sep 2026
FromEUR246*
Last update 1 day ago
Flight Type Round Trip/Economy
Oct 2026
FromEUR246*
Last update 5 hrs ago
Flight Type Round Trip/Economy
cmp-daily-histogram-bars-legend-min-price-aria-label EUR246
cmp-daily-histogram-bars-legend-max-price-aria-label EUR604
Displaying fares for August-2026
  • LYS–IST, Fri, August 28 – Fri, September 11: From EUR531
    28

    Fr

    AUG

  • LYS–IST, Sat, August 29 – Sat, September 12: From EUR447
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  • LYS–IST, Sun, August 30 – Sun, September 13: From EUR604
    30

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  • LYS–IST, Mon, August 31 – Mon, September 14: From EUR407
    31

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  • LYS–IST, Tue, September 01 – Tue, September 15: From EUR385
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    SEP

  • LYS–IST, Wed, September 02 – Wed, September 16: From EUR466
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  • LYS–IST, Thu, September 03 – Thu, September 17: From EUR372
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  • LYS–IST, Fri, September 04 – Fri, September 18: From EUR385
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  • LYS–IST, Sat, September 05 – Sat, September 19: From EUR469
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    Sa

  • LYS–IST, Sun, September 06 – Sun, September 20: From EUR541
    06

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  • LYS–IST, Mon, September 07 – Mon, September 14: From EUR407
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  • LYS–IST, Tue, September 08 – Tue, September 15: From EUR372
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  • LYS–IST, Wed, September 09 – Wed, September 23: From EUR447
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  • LYS–IST, Thu, September 10 – Thu, September 24: From EUR407
    10

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  • LYS–IST, Fri, September 11 – Tue, September 15: From EUR385
    11

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  • LYS–IST, Sat, September 12 – Wed, September 30: From EUR372
    12

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  • LYS–IST, Sun, September 13 – Sun, September 27: From EUR395
    13

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  • LYS–IST, Mon, September 14 – Fri, September 18: From EUR469
    14

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  • LYS–IST, Tue, September 15 – Sat, September 19: From EUR372
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  • LYS–IST, Wed, September 16 – Wed, September 30: From EUR282
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  • LYS–IST, Thu, September 17 – Thu, October 01: From EUR246
    17

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  • LYS–IST, Fri, September 18 – Fri, October 02: From EUR282
    18

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  • LYS–IST, Sat, September 19 – Sat, October 03: From EUR246
    19

    Sa

  • LYS–IST, Sun, September 20 – Thu, September 24: From EUR384
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  • LYS–IST, Mon, September 21 – Mon, September 28: From EUR295
    21

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  • LYS–IST, Tue, September 22 – Tue, October 06: From EUR246
    22

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  • LYS–IST, Wed, September 23 – Thu, October 01: From EUR246
    23

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  • LYS–IST, Thu, September 24 – Thu, October 01: From EUR282
    24

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  • LYS–IST, Fri, September 25 – Fri, October 02: From EUR259
    25

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  • LYS–IST, Sat, September 26 – Sat, October 10: From EUR246
    26

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  • LYS–IST, Sun, September 27 – Thu, October 01: From EUR251
    27

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    • RangeEUR246-EUR604

    *Fares displayed have been collected within the last 48 hours and may no longer be available at the time of booking. Learn more about this offer. Additional fees and charges for optional products and services may apply.

    Destination 1

    Departure: Lyon

    Set on an island in the middle of the Rhone and Saone rivers, Lyon offers a relaxed atmosphere away from the Paris tourist circuit. Lyon is a genuine gourmet capital, and its famous Bouchon cuisine is worth discovering, while each corner of the city showcases homegrown cultural and literary elements such as Puppet Guignol and The Little Prince. As France's third largest city and a former capital of the silk trade, Lyon was designated a UNESCO World Heritage Site in 1998, a testament to its aesthetic architecture and historical significance. Some Lyon highlights include Fourviere Hill, accessed via a delightful funicular ride; the mysterious Croix Rousse, with more than 400 secret passages; Notre Dame de Fourviere Basilica; and Le Petit Musée Fantastique de Guignol.

    Arrival: Istanbul

    Turkish Airlines offers direct flights from Lyon to Istanbul, an ancient city whose beauty spans two continents. Flights take around three hours and 20 minutes. Istanbul, one of the world's most popular tourist destinations, welcomes millions of visitors each year, who come to view the city’s historic structures and bask in its cosmopolitan atmosphere. Some of Istanbul’s most notable highlights include the magnificent Hagia Sophia; Topkapı Palace, one of the Ottoman Empire's emblematic complexes; the Süleymaniye Mosque, a masterpiece by Mimar Sinan; and the Grand Bazaar, among the world's oldest and largest markets. We recommend visiting the Beyoğlu, Nişantaşı and Kadıköy neighborhoods to experience Istanbul's modern face and a culinary culture that embraces everything from street snacks to Michelin-starred restaurants.

    Destination 1

    Discover Lyon - Istanbul flights

    View current Lyon – Istanbul flight ticket fares to find the flight that’s best for you. Whether you’re flying for business or for leisure, you’ll enjoy a safe, comfortable trip with the exceptional service standards offered by Turkish Airlines.

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    Discover Lyon - Istanbul flights
    From
    To
    Fare Type
    Dates
    Price
    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Sat, October 10 - Wed, October 14

    From

    EUR246

    Last update 5 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Wed, September 23 - Thu, October 01

    From

    EUR246

    Last update 21 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Thu, October 08 - Mon, October 12

    From

    EUR246

    Last update 14 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Tue, October 27 - Tue, November 10

    From

    EUR246

    Last update 14 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Tue, September 29 - Tue, October 06

    From

    EUR246

    Last update 14 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Wed, December 02 - Wed, December 16

    From

    EUR246

    Last update 14 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Sat, November 07 - Wed, November 11

    From

    EUR246

    Last update 14 hrs ago

    Lyon (LYS)Istanbul (IST)Round-trip
    /
    Economy    		Mon, November 30 - Mon, December 07

    From

    EUR246

    Last update 14 hrs ago

    *Fares displayed have been collected within the last 48 hours and may no longer be available at time of booking.

    Airport information

    Lyon-Saint Exupéry Airport (LYS)

    Turkish Airlines operates Lyon-Istanbul flights from Lyon-Saint Exupéry Airport (LYS). The airport is about 25 kilometers from the city center and accessible via metro, bus or taxi, as well as private vehicle or car sharing. Rhônexpress trains and bus lines 47 and 48 operate between the Lyon city center and the airport.

    Istanbul Airport (IST)

    Located in Arnavutköy, on Istanbul's European side, Istanbul Airport is approximately 42 kilometers from the Istanbul city center. After landing at the airport from Lyon, you can reach the city center via the metro, taxis, municipal buses or airport shuttle buses or by renting a car. The IETT buses, numbered H-1, H-2, H-3, H-6, H-8, and the Gayrettepe - Istanbul Airport metro (M11) are convenient public transportation options operating between the airport and the city, as are the Havaist airport shuttles, which offer service to Istanbul Airport. Taxis are available 24-7 at the airport; the fare and length of the ride will depend according to your destination. In addition, you can rent a car at the airport.

    Frequently Asked Questions